Praziquantel 98.5% 99% USP BP EP CAS 55268-74-1

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    2018-06-19 20:38

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Product details

Praziquantel 98.5% 99% USP BP EP CAS 55268-74-1                                             

Product Name: Praziquantel

Synonyms:  Praziquandone  /  Praziquandon /  Praziquantelum / Prazikvantel

CAS Number: 55268-74-1

Characteristics: White crystalline powder or similar powder.

Assay: 98.5% ~ 101%, 99%

Formula: C19H24N2O2

Package: 25Kg/

 

Description:

Praziquantel is an effective anthelmintic or anti-worm medication which is used in treatment for most schistosome and many cestode infestations.

Praziquantel powder raw material will prevent newly hatched insect larvae (worms) from growing or multiplying in the system.

Praziquantel effects the permeability of the cell membrane resulting in the contraction of schistosomes. Praziquantel powder will further cause vacuolization and disintegration of the schistosome tegument. This effect is more marked on adult worms compared to young worms. An increased calcium influx will play a big role. Secondary effects of Praziquantel include inhibition of glucose uptake, lowering of glycogen levels and stimulation of lactate release. Please do note that the effect of praziquantel is limited very specifically to trematodes and cestodes; nematodes (including filariae) are not affected, it won’t work.

 

Praziquantel Mechanism of Action

Praziquantel causes severe spasms and paralysis of the worms' muscles. This effect is accompanied - and probably caused - by a rapid Calcium influx inside the schistosome. Morphological alterations are another early effect of praziquantel. These morphological alterations are accompanied by an increased exposure of schistosome antigens at the parasite surface. The worms will be either completely destroyed in the intestine or pass in the stool. The effective period can be 3-7 weeks. Glutathione S-transferase, which is an important detoxification enzyme in parasitic helminths, is the main vaccine target and a praziquantel target against schistosomiasis.

 

Fengchen Group is a leading supplier of Praziquantel Powder Raw Material from China. We specialize in wholesale and bulk amounts, ensuring all our clients have the right supplier of Triethylenediamine powder when they need it. When you are going to buy or purchase Praziquantel Powder Raw Material or API, please turn to Fengchen Group. 


Usage: Praziquantel  is Anthelmintic substance. Mostly, it will be made to Praziquantel Tablets.

It will prevent newly hatched insect larvae (worms) from growing or multiplying in human or animal body. Praziquantel is used to treat infections caused by Schistosoma worms.

There is also a big range of using for making veterinary medicines. 

Praziquantel is widely used to treat infections caused by Schistosoma worms, which will get into the body through skin that has come into contact with contaminated water. Praziquantel is also used to treat infection with liver flukes, caused by worms. However, Praziquantel powder raw material should not be used to treat parasitic infections in the eye. 


Technical Indexes:

Name   of Product

Praziquantel

Testing Item

Standard

Result

Loss   on drying

≤   0.5%

0.12%

Residue   on Ignition

≤   0.1%

0.05%

Heavy   Metal(ppm)

≤   20ppm

<   20ppm

Melting   Point-- Praziquantel

136.0-142.0

137.4-140.5

Phosphate

≤   0.05

<   0.05

Residual   Solvents

Chloroform≤   60ppm

Not   detected

Acctonc≤   5000ppm

555ppm

Related   Compounds

A≤   0.2

0.11

B≤   0.2

0.09

C≤   0.2

0.01

Assay   (Praziquantel)

98.5%   ~ 101.0%

99.36%





PREGNANCY:

Praziquantel  has been tested in breeding and pregnant dogs and cats. No adverse effects were noted.

STORAGE CONDITIONS: Store at or below 25ºC.


Top Quality, Pure Praziquantel Powder;  Praziquantel  Raw Material Supplier in China. Praziquantel API Manufacturer. 

 

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